Possible mechanisms of homocysteine toxicity
نویسندگان
چکیده
منابع مشابه
Molecular mechanisms of homocysteine toxicity and possible protection against hyperhomocysteinemia
Homocysteine is a naturally occurring intermediate connecting metabolism of methionine and cysteine and, subsequently glutathione. Its normal level in mammalian blood does not exceed 10 μmol/l, whereas vitamin deficient diet, increased stationary levels of reactive oxygen species, as well as neurodegenerative and cardiovascular diseases are usually accompanied by an increased content of homocys...
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Maternal smoking has been recognized as a common cause of low birth weight, preterm birth and the decrease of gestational age period. Unfortunately, there is an increasing interest within public especially woman in Iran in the tobacco products consumption. On the other hand, the deleterious effect of maternal smoking on human fetus in pregnancy period especially in the first trimester encourage...
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Increased blood plasma concentrations of the sulphur amino acid homocysteine ("homocysteinemia") have been brought into context with neurodegenerative and arteriosclerotic symptoms and diseases. We recently reported on biochemical model reactions on the prooxidative activity of homocysteine including the desactivation of Na+/K(+)-ATPases and hemolysis of erythrocytes (Preibisch et al., 1993). I...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2003
ISSN: 0085-2538
DOI: 10.1046/j.1523-1755.63.s84.33.x